Status:
COMPLETED
Glucose Metabolism During Hemodialysis
Lead Sponsor:
Bo Feldt-Rasmussen
Conditions:
ESRD
Eligibility:
All Genders
18-90 years
Brief Summary
Disturbed glucose metabolism is a common feature of patients with end-stage renal disease (ESRD). Several hormones responsible of a stable blood glucose including insulin, glucagon, and the gastrointe...
Detailed Description
BACKGROUND Disturbed glucose metabolism is a common feature of patients with end-stage renal disease (ESRD). Furthermore, the prevalence of diabetes mellitus in the ESRD population is high resulting ...
Eligibility Criteria
Inclusion
- Aged 18-90 years
- Dialysis-dependent ESRD for more than 3 months
- Regular treatment with either hemodialysis or hemodiafiltration
- A well functioning arteriovenous fistula
- Fistula flow ≥ 400 ml/min
Exclusion
- Diabetes mellitus
- Impaired fasting glucose (fasting plasma glucose ≥ 6.1 mmol/l)
- Current illness requiring admission to the hospital
- Significant acidosis before dialysis (standardized bicarbonate \< 20 mmol/l)
- Anemia (B-Hemoglobin \< 6,0 mmol/l)
- Known allergy to Paracetamol
- Medical treatment with compounds of known diabetogenic and / or insulin secretion inhibitory effect, including steroids and calcineurin inhibitors.
- Bowel resection or other major surgery of the gastrointestinal tract
- Current malignancy not including basal cell carcinoma
Key Trial Info
Start Date :
February 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT01800188
Start Date
February 1 2013
Last Update
November 19 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Nephrology department, Rigshospitalet
Copenhagen, Copenhagen, Denmark, 2100