Status:

COMPLETED

Study of Meloxicam Capsules in Subjects With Osteoarthritis of the Knee or Hip

Lead Sponsor:

Iroko Pharmaceuticals, LLC

Conditions:

Osteoarthritis

Eligibility:

All Genders

40+ years

Phase:

PHASE3

Brief Summary

The purpose of this study is to evaluate the safety of Meloxicam SoluMatrix Capsules for up to 52 weeks in subjects with pain due to osteoarthritis (OA) of the knee or hip

Eligibility Criteria

Inclusion

  • Is male or female ≥ 40 years of age
  • If a participant in the previous MEL3-12-02 study, completed the study and did not discontinue for lack of efficacy or safety
  • Has a diagnosis of OA of the hip or knee with ongoing knee and/or articular hip pain
  • Chronic user of nonsteroidal anti-inflammatory drugs (NSAIDs) and/or acetaminophen for OA pain
  • If female and of childbearing potential, is nonlactating and nonpregnant

Exclusion

  • History of allergic reaction or clinically significant intolerance to acetaminophen, aspirin, or any NSAIDs, including meloxicam
  • Requires continuous use of opioid or opioid combination products to control OA pain of the knee or hip
  • Clinically significant unstable cardiac, respiratory, neurological, immunological, hematological, or renal disease
  • Significant difficulties swallowing capsules or unable to tolerate oral medication
  • Has received any investigational drug (except Meloxicam SoluMatrix Capsules), device, or therapy within 30 days before Screening

Key Trial Info

Start Date :

March 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2014

Estimated Enrollment :

600 Patients enrolled

Trial Details

Trial ID

NCT01801735

Start Date

March 1 2013

End Date

August 1 2014

Last Update

May 12 2015

Active Locations (40)

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Page 1 of 10 (40 locations)

1

Birmingham, Alabama, United States, 35216

2

Phoenix, Arizona, United States, 85053

3

Carmichael, California, United States, 95608

4

Pismo Beach, California, United States, 93449