Status:

COMPLETED

A Pilot Study of Activated T Cell Therapy for Refractory/Relapsed Neuroblastoma

Lead Sponsor:

Seoul National University Hospital

Conditions:

Neuroblastoma

Eligibility:

All Genders

Up to 21 years

Phase:

NA

Brief Summary

Activated T cell were manufactured through in vitro T cell expansion of autologous T cell. We designed this study to determine the feasibility and safety of Activated T-lymphocyte cell therapy for ref...

Eligibility Criteria

Inclusion

  • Informed consent
  • Age 21 years or younger
  • Histologically confirmed neuroblastoma
  • Progressive disease after standard treatment or relapsed patient
  • ECOG scale (ECOG-PS) ≤2
  • Expected survival at least 3 months

Exclusion

  • Patients with autoimmune disease
  • Patients with immunodeficiency
  • Other malignancy 5 year prior to this study
  • Severe organ dysfunction
  • Severe allergic disease
  • Severe psychiatric disorder
  • Pregnancy or lactating woman

Key Trial Info

Start Date :

February 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 31 2018

Estimated Enrollment :

6 Patients enrolled

Trial Details

Trial ID

NCT01802138

Start Date

February 1 2013

End Date

October 31 2018

Last Update

April 9 2019

Active Locations (1)

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1

Seoul National University Hospital

Seoul, Chongno-gu, South Korea