Status:
COMPLETED
Longitudinal Therapeutically Non-interventional Study of MSRV-Env Burden in Patients With Multiple Sclerosis Disease
Lead Sponsor:
GeNeuro Innovation SAS
Conditions:
Multiple Sclerosis (MS)
Relapsing-Remitting MS
Eligibility:
All Genders
18-60 years
Brief Summary
This study intends to explore evolution of MSRV expression by analyzing the levels of MSRV transcripts in blood, as well as the levels of the MSRV-Env protein in serum of MS patients. The study will b...
Eligibility Criteria
Inclusion
- Signature of an informed consent;
- Male or female between 18 and 60 years of age;
- Patients with PPMS (Revised McDonald criteria 2010) or patients with SPMS or CIS or patients with RRMS (Revised McDonald criteria 2010) ideally without IFN beta therapy at the T0 visit for RRMS patient only.
Exclusion
- Positive serology for hepatitis B or C or HIV;
- Acute infection at inclusion;
- Severe psychiatric disorder;
- Autoimmune disease other than MS;
- Pregnancy or breastfeeding;
- Heavy smokers i.e. more than 10 cigarettes per day;
- History of alcohol or drug abuse in the last 3 years;
- Participation in a clinical trial (within the last 3 months).
Key Trial Info
Start Date :
November 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2015
Estimated Enrollment :
58 Patients enrolled
Trial Details
Trial ID
NCT01804647
Start Date
November 1 2012
End Date
February 1 2015
Last Update
October 20 2020
Active Locations (4)
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1
Hospices civils de Lyon - Service de Neurologie A - 59 Boulevard Pinel
Bron, France, 69677
2
CHU Timone - Service de Neurologie et CRMBM CNRS 7339 - 264, rue Saint Pierre
Marseille, France, 13385
3
Hospital Universitari and Research Institute Vall d'Hebron - Servicio de Neuroimunologia de Nuestro Centro - Pg. Vall d'Hebron 119-129
Barcelona, Catalonia, Spain, 08035
4
Centre Hospitalier Universitaire Vaudois - Dpt of Clinical Neurosciences - Neurology /Batiment 10-131 - Rue du Bugnon 46 -
Lausanne, Switzerland, CH-1011