Status:
COMPLETED
Laparoscopic Ovarian Cystectomy of Endometrioma vs Deroofing and Ovarian Reserve
Lead Sponsor:
Ain Shams University
Conditions:
Endometrioma
Eligibility:
FEMALE
18-35 years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate the impact of laparoscopic ovarian cystectomy versus laparoscopic cyst deroofing on ovarian reserve measured by serum levels of anti mullerian hormone and antr...
Detailed Description
One of the major concerns about excision of endometriomas is their negative effect on ovarian reserve because of follicle loss, removal of endometriomas has been associated with poorer performance in ...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Age from 18-35 year
- Regular menstrual cycles.
- Endometrioma (unilateral or bilateral) diagnosed by transvaginal ultrasound with diameter ≥ 3 cm.
- Exclusion criteria:
- Any previous ovarian surgery.
- Evidence of polycystic ovary syndrome according to Rotterdam criteria
- Two of three of:
- Oligo- or chronic anovulation.
- Clinical and/or biochemical signs of hyperandrogenism.
- Polycystic ovaries.
- Evidence of premature ovarian failure diagnosed by follicle stimulating hormone level ≥40 IU/L
- Any endocrinal disease affecting ovarian function e.g. thyroid dysfunction, hyperprolactinemia.
- Previous hormonal medications e.g. oral contraceptive pills, gonadotropin-releasing hormone analogue within the last 3 months before surgery.
- Any suspicious findings of ovarian malignant diseases diagnosed by transvaginal ultrasound.
- Contraindication to surgery.
Exclusion
Key Trial Info
Start Date :
March 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2014
Estimated Enrollment :
122 Patients enrolled
Trial Details
Trial ID
NCT01808170
Start Date
March 1 2013
End Date
August 1 2014
Last Update
March 26 2015
Active Locations (1)
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1
Ain Shams University Maternity Hospital
Cairo, Egypt