Status:

COMPLETED

Comparison Study of ISV-303 to Durasite Vehicle in Cataract Surgery Subjects

Lead Sponsor:

Sun Pharmaceutical Industries Limited

Conditions:

Ocular Inflammation

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The purpose of this study is to evaluate the ocular safety, tolerability and efficacy of topical administration of ISV-303 compared with Durasite Vehicle.

Eligibility Criteria

Inclusion

  • Male or female subjects age 18 or older scheduled for unilateral cataract surgery with posterior chamber intraocular lens implantation
  • If a female is of childbearing potential, the subject must agree to and submit a negative pregnancy test before any protocol-specific procedures are conducted. The subject must use effective contraception for the duration of the study. Post menopausal is defined as having no menses for at least 12 consecutive months
  • Signature of the subject on the Informed Consent Form
  • Willing to avoid disallowed medications for the duration of the study
  • Willing and able to follow all instructions and attend all study visits
  • Able to self-administer the IMP (or have a caregiver available to instill all doses of study drugs )
  • Additional inclusion criteria also apply

Exclusion

  • Known hypersensitivity or poor tolerance to bromfenac sodium or any component of the IMP or any of the procedural medications
  • Currently pregnant, nursing, or planning a pregnancy; or be a woman that has a positive pregnancy test
  • Currently suffer from alcohol and/or drug abuse
  • Prior (within 30 days of beginning study treatment) or anticipated concurrent use of an investigational drug or device
  • A condition or a situation, which in the investigator's opinion may put the subject at increased risk, confound study data, or interfere significantly with the subject's study participation
  • Additional inclusion criteria also apply

Key Trial Info

Start Date :

May 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2013

Estimated Enrollment :

268 Patients enrolled

Trial Details

Trial ID

NCT01808547

Start Date

May 1 2013

End Date

November 1 2013

Last Update

November 19 2021

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