Status:
COMPLETED
Thrombospondin-1 and Pigmented Epithelium Derived Factor Levels in Patients With Diabetes Mellitus.
Lead Sponsor:
MidAtlantic Retina
Conditions:
Diabetes
Diabetes Mellitus
Eligibility:
All Genders
18+ years
Brief Summary
You are being asked to be in a research study to determine blood levels and vitreous levels of compounds called thrombospondin 1 (TSP1) and pigment epithelium derived factor (PEDF). These compounds ex...
Detailed Description
The hypothesis tested here is that diabetic patients that express the higher molecular weight pigment epithelium-derived factor (PEDF) isoform have lower thrombospondin-1 (TSP1) level and, as a result...
Eligibility Criteria
Inclusion
- Ability to provide written informed consent and comply with study assessments for the full duration of the study
- Diabetes Mellitus
- Undergoing pars plana vitrectomy for any reason
Exclusion
- Use of any anti-VEGF (vascular endothelial growth factor ) medications
Key Trial Info
Start Date :
March 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2014
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT01809093
Start Date
March 1 2010
End Date
March 1 2014
Last Update
February 23 2017
Active Locations (1)
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1
Mid Atlantic Retina- Wills Eye Institute
Philadelphia, Pennsylvania, United States, 19107