Status:

COMPLETED

Prevention of Hepatitis B Virus Mother-to-child Transmission by Serovaccination.

Lead Sponsor:

Hopital Lariboisière

Conditions:

Hepatitis B

Eligibility:

FEMALE

18-45 years

Brief Summary

The prevalence of HBsAg carriage in pregnant women varies in France, according to the native country, with highest rates in those originating from sub-Saharan Africa and Asia (5 to 8 % in Parisian are...

Detailed Description

This monocentre, observational study will include pregnant women whom HBV-DNA is \> 105 IU/mL. HBV MTCT rates will be evaluated, according to the level of HBV-DNA in the women during the last three mo...

Eligibility Criteria

Inclusion

  • Pregnant woman
  • whom HBs Ag +
  • whom HBV-DNA \>105 IU/mL

Exclusion

  • Women who have to be treated for HBV hepatitis, (AST/ALT \>2 ULN without any explanation, liver biopsy performed before pregnancy showing hepatitis requiring initiation of treatment)

Key Trial Info

Start Date :

November 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 1 2013

Estimated Enrollment :

28 Patients enrolled

Trial Details

Trial ID

NCT01810835

Start Date

November 1 2011

End Date

November 1 2013

Last Update

December 6 2013

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Hopital Lariboisiere

Paris, France, 75475

2

Paris, France