Status:

COMPLETED

Methyl-Donors and EpiGenetics in The Gambia

Lead Sponsor:

Medical Research Council

Conditions:

Aberrant DNA Methylation

Eligibility:

All Genders

1-45 years

Brief Summary

Accumulating evidence suggests that early-life nutrition can affect metabolism and thus increase the risk of disease in adulthood (e.g. type II diabetes and obesity). One possible mechanism to explain...

Eligibility Criteria

Inclusion

  • Inclusion criteria women:
  • \- women aged 18-45 years on 15th March 2009, resident in West Kiang
  • Exclusion criteria women:
  • on contraception
  • confirmed pregnancy at recruitment
  • enrolment in any study other than the ENID (Early Nutrition and Immune Development) trial (ISRCTN49285450)
  • suffering from severe anaemia (haemoglobin \<7 g/dl) or known sickle cell disease
  • Inclusion criteria infants:
  • \- born to the above women
  • Exclusion criteria infants:
  • \- those known to be severely malnourished (weight-for-height Z-score \< -3)

Exclusion

    Key Trial Info

    Start Date :

    January 1 2009

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    December 1 2015

    Estimated Enrollment :

    166 Patients enrolled

    Trial Details

    Trial ID

    NCT01811641

    Start Date

    January 1 2009

    End Date

    December 1 2015

    Last Update

    March 22 2016

    Active Locations (0)

    Enter a location and click search to find clinical trials sorted by distance.

    Page 1 of 0 (0 locations)

    No Results Found

    We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.