Status:
COMPLETED
Combination Iodine 125 Seed Implants and LHRH Agonists for Locally Advanced (Stage T3) Prostate Cancer
Lead Sponsor:
Chinese PLA General Hospital
Conditions:
Prostate Cancer
Eligibility:
All Genders
Brief Summary
Patients with prostate cancer should have the following examination including biopsy, serum PSA volume, prostate CT scan or MRI, bone scan, abdomen ultrasound, chest X ray, blood biochemistry, blood r...
Eligibility Criteria
Inclusion
- Provision of written informed consent
- T2c-T3b N0 M0 (biopsy、 bone scan、 CT、 MRI)
- No Metastasis (bone scan、 CT、 MRI)
- PSA level\>10ng/ml
- Histological or cytological confirmation of prostate cancer
- Able to understand and comply with the requirements of the study
Exclusion
- Having been treated with external radiation therapy or chemistry therapy.
- Clinical relevant disease and/or abnormalities (past or present), eg, significant cardiovascular, renal or liver disease, malignancy, gastro-intestinal disorders, or other conditions which could affect the absorption/elimination of drugs.
- Alanine amino transferase (ALT) or aspartate amino transferase (AST) greater than 2 times the upper limit of normal (ULN) at screening findings that make it undesirable for the patient to participate in the study in the opinion of the investigator(s)
- In the opinion of the investigator(s), any evidence of severe or uncontrolled systemic disease (eg, currently unstable or unresolved respiratory, cardiac, hepatic, or renal disease).
- Contra-indications (eg, known or suspected allergy) to GnRH antagonists or excipients(non-active ingredients of investigational product).
- Treatment with a non-approved or investigational drug within 30 days before study entry.
- Bibulosity or drug abuse.
Key Trial Info
Start Date :
February 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT01813097
Start Date
February 1 2008
Last Update
March 18 2013
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.