Status:
COMPLETED
Safety and Efficacy of Nonsteroidal Antiinflammatory (NSAI)Drug and Glucocorticoids in Acute Sciatica
Lead Sponsor:
University Hospital, Grenoble
Conditions:
Sciatica
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine whether anti-inflammatory drugs or glucocorticoids are effective in the treatment of acute sciatica
Eligibility Criteria
Inclusion
- sciatica \<8 weeks resistant to all treatments in ambulatory
- Acute low back pain\> 48 hours;
- Non-deficit patients;
- Initial VAS\> 40/100;
- Consent of patient
- Conflict disco-radicular concordance with the clinical computed tomography scan or magnetic resonance imaging.
- No of contraindications to methylprednisolone, ketoprofen;
- No registration to another protocol;
Exclusion
- Pregnant, parturient, lactating mother;
- Diabetic patient;
- Patient with syndrome from narrowing of the lumbar vertebral canal
- Patient with a history of lumbar surgery \<1 year;
- Patient with a Cauda equina syndrome or major motor disability;
- Crural neuralgia
- Patient with a deficit;
- Suspicion of sciatica secondary, ie not conflict-related disco-root: infectious neuritis, fracture on spinal bone tumor ...
- associated treatment or pathology contra-indicating administration methylprednisolone, ketoprofen.
Key Trial Info
Start Date :
January 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2016
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT01816334
Start Date
January 1 2013
End Date
January 1 2016
Last Update
March 24 2016
Active Locations (2)
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1
CHU Hôpital Sud
Échirolles, France, 38130
2
CH d'Uriage
Uriage-les-Bains, France, 38410