Status:
COMPLETED
Effect of Isoflurane on Tissue Doppler Imaging of Mitral Annulus During Cardiac Surgery
Lead Sponsor:
Konkuk University Medical Center
Conditions:
Valvular Heart Disease
Ischemic Heart Disease
Eligibility:
All Genders
20-65 years
Phase:
NA
Brief Summary
The purpose of this study is to determine Isoflurane's dose-dependent effect on left ventricular (LV) systolic function in cardiac surgery. The change of tissue Doppler imaging (TDI) of lateral mitral...
Detailed Description
Isoflurane is widely used in cardiac surgery patients due to its beneficial effects, but many studies have shown that isoflurane reduces myocardial contractility in a dose-dependent manner, and compro...
Eligibility Criteria
Inclusion
- patients undergoing cardiac surgery
Exclusion
- low ejection fraction \< 50% in preoperative transthoracic echocardiography
- atrial fibrillation
- pacemaker
- pericardial and infiltrative myocardial disease
- mitral annular calcification, surgical rings, prosthetic mitral valves
- lateral left ventricular regional wall motion abnormality
- esophageal spasm, stricture, laceration, perforation, and diverticulum diaphragmatic hernia
- history of extensive radiation to mediastinum
- upper gastrointestinal bleeding
Key Trial Info
Start Date :
March 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2014
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT01819012
Start Date
March 1 2013
End Date
March 1 2014
Last Update
November 2 2016
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Konkuk University Medical Center
Seoul, Seoul, South Korea, 143-729