Status:
COMPLETED
Effects of Lansoprazole on Sitagliptin Glucose-lowering Ability in Healthy Males: a Randomised Crossover Study
Lead Sponsor:
Xijing Hospital
Conditions:
Healthy
Eligibility:
MALE
18-50 years
Phase:
PHASE1
Brief Summary
Oral hypoglycemic medications sometimes do not control type 2 diabetes well. Proton pump inhibitors (PPIs) as adjunctive therapy might improve diabetes control and could enhance the hypoglycemic activ...
Detailed Description
Oral hypoglycemic medications sometimes do not control type 2 diabetes well. Proton pump inhibitors (PPIs) as adjunctive therapy might improve diabetes control and could enhance the hypoglycemic activ...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- General good health condition
- Male subject, between 18 and 50 years
- Exclusion Criteria
- Overweight (Body Mass Index ≥30)
- Metabolic disorders
- History of gastrointestinal disorders
- Regular (daily) intake of medication
- Smoking more than 10 cigarettes/day
- History of drug abuse
- Exhaustive (\> 3 units/day) alcohol consumption
- Exhaustive (\> 5 units/day) caffeine consumption (coffee, tea, cola, or other caffeine based drinks)
- Recent (in the last 14 days) donation of blood
- Recent (in the last 2 days) donation of blood plasma
- Participation in another trial within 4 weeks before the start of the study
Exclusion
Key Trial Info
Start Date :
March 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2013
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT01820104
Start Date
March 1 2013
End Date
May 1 2013
Last Update
May 3 2013
Active Locations (1)
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1
Department of pharmacy, Xijing Hospital, Fourth Military Medical University
Xi'an, Shaanxi, China