Status:
COMPLETED
The Therapeutic Role of Intravenous Albumin Administration for Peptic Ulcer Bleeding Patients With Hypoalbuminemia
Lead Sponsor:
National Cheng-Kung University Hospital
Collaborating Sponsors:
National Science and Technology Council, Taiwan
Conditions:
Peptic Ulcer Bleeding
Hypoalbuminemia
Eligibility:
All Genders
39-83 years
Phase:
PHASE4
Brief Summary
To test whether intravenous albumin can decrease the rebleeding rate or shorten the duration of hospitalization in patients with peptic ulcer bleeding and hypoalbuminemia.
Detailed Description
Peptic ulcer bleeding is a common but potentially lethal disease. Recurrent bleeding is an independent risk factor for mortality. Inhibition of gastric acid secretion by intravenous proton pump inhibi...
Eligibility Criteria
Inclusion
- Clinical presentations of melena, hematochezia, or hematemesis
- Gastroscopy confirmed peptic ulcers and major stigmata of recent hemorrhage
- A Rockal score ≥ 6
Exclusion
- Gastric or esophageal, or duodenal tumor bleeding
- Ulcer due to mechanical factors
- Warfarin use
- Failure to establish hemostasis under gastroscopy
- Hypersensitivity to omeprazole, esomeprazole, albumin or any component of the formulation.
Key Trial Info
Start Date :
January 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2011
Estimated Enrollment :
91 Patients enrolled
Trial Details
Trial ID
NCT01822600
Start Date
January 1 2010
End Date
August 1 2011
Last Update
August 29 2019
Active Locations (1)
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1
National Cheng Kung University Hospital
Tainan, Taiwan, 704