Status:
COMPLETED
Study on Visual Function Impairments in Dry Age-related Macular Degeneration
Lead Sponsor:
Duke University
Collaborating Sponsors:
Hoffmann-La Roche
Conditions:
Age Related Macular Degeneration
Eligibility:
All Genders
50+ years
Brief Summary
The study hypothesis is that patients with dry age-related macular degeneration experience visual function impairments such as defects in dark adaptation, glare intolerance, poor light transition and ...
Detailed Description
This prospective, exploratory study will be performed in multiple arms: A. Arm 1: a pilot study of up to 40 patients (30 patients with dry age-related macular degeneration and 10 normal age-matched c...
Eligibility Criteria
Inclusion
- Capable and willing to provide consent
- Has been diagnosed with dry age-related macular degeneration stages 1-3
- At least 50 years of age
Exclusion
- Unable or unwilling to give consent
- Under 50 years of age
- Presence of retinal pathology such as central geographic atrophy, hemorrhage or retinal fluid, and other macular pathology other than AMD
- Presence of dense cataracts in the study eye(s) that can affect visual function tests
- Presence of glaucoma requiring treatment during the study and/or visual field defects
- Presence retinal laser or surgical theraphy in study eye (s)
- Any of other ocular condition requiring long-term theraphy or surgery during the study
- Participant has photographically significant corneal or media opacities in either eye that would preclude adequate ophthalmic imaging and functional testing
- Diagnosis of nystagmus that will interfere with testing
- High myopia -8 Diopters or more severe
- Participant has, in the opinion of the Investigator, any physical or mental condition that would increase the risk of participation in the stduy or may interfere with the study procedures, evaluations and outcome assessments.
Key Trial Info
Start Date :
March 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2018
Estimated Enrollment :
128 Patients enrolled
Trial Details
Trial ID
NCT01822873
Start Date
March 1 2013
End Date
July 1 2018
Last Update
April 17 2019
Active Locations (1)
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1
Duke Eye Center
Durham, North Carolina, United States, 27710