Status:
COMPLETED
Circulating Anti-Beta2-glycoprotein Antibodies and Endothelial Dysfunction
Lead Sponsor:
Hospital Universitario Getafe
Conditions:
Peripheral Arterial Disease
Eligibility:
MALE
18-90 years
Brief Summary
Circulating anti-beta2-glycoprotein antibodies have been associated with coronary artery disease and peripheral arterial disease. This auto-antibodies could activate endothelial cells leading to the e...
Eligibility Criteria
Inclusion
- Male gender
- Peripheral arterial disease diagnosis
- Intermittent claudication.
- Hemodynamic confirmation of the disease through non-invasive vascular studies.
Exclusion
- Autoimmune disease
- Previous revascularization of the ischemic limb.
- Ischemic ulcers
- Previous history of organ transplants.
- Treatment with immunosuppressors
Key Trial Info
Start Date :
February 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2012
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT01822990
Start Date
February 1 2011
End Date
July 1 2012
Last Update
April 4 2013
Active Locations (1)
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1
Hospital Universitario de Getafe
Getafe, Madrid, Spain, 28905