Status:
SUSPENDED
Effect of Increasing Motor Cortex Inhibition on Task Specific Dystonia
Lead Sponsor:
Emory University
Conditions:
Dystonia
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Dystonia is a disease where muscles in the affected body part are abnormally active. This may result in abnormal postures. The underlying mechanisms are not known. One proposed mechanism is located in...
Eligibility Criteria
Inclusion
- If you are treated with Botulinum toxin, the testing should be done at least 3 months after your last Botulinum toxin injections.
- Adult patients with task-specific dystonia strictly confined to one hand since the onset of symptoms
- No dystonic movements at rest
- Normal MRI scan of the brain as per clinical record
- No intake of CNS active drugs that may interfere with the study
- No contraindication for TMS
- Ability to perform the selective task
- No other neurological disease that may interfere with the study
- Ability to give informed consent
Exclusion
- You have a history of migraines
- You have a diagnosed seizure disorder
- You take any Central Nervous System CNS active drugs, such as benzodiazepines, Lorazepam, Baclofen, SSRI's and other anti-depressants, etc. that may interfere with the response to TMS.
- You have any clips or implants in your head
- You have a pacemaker
Key Trial Info
Start Date :
February 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2024
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT01823237
Start Date
February 1 2013
End Date
February 1 2024
Last Update
August 16 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Emory University School of Medicine
Atlanta, Georgia, United States, 30322