Status:
COMPLETED
Xylitol Disk Use in Adults With Dry Mouth
Lead Sponsor:
University of Washington
Conditions:
Mutans Streptococci
Xerostomia
Eligibility:
All Genders
21+ years
Phase:
NA
Brief Summary
The purpose of this study is to demonstrate whether decay causing bacteria are reduced when adhesive xylitol disks are used intraorally three times a day for two weeks in adults with dry mouth.
Detailed Description
Xylitol,an FDA approved sugar substitute, has been shown to reduce tooth decay. Patients who experience dry mouth may be more susceptible to dental decay because they lack the protection provided by a...
Eligibility Criteria
Inclusion
- Adults 21 years old or older
- Daily use of at least 2 prescription medications known to cause dry mouth
- Current report of dry mouth
Exclusion
- Antibiotic use in the last month
- Topical oral antimicrobial (e.g. Chlorhexidine rinse) use in the last month
- Change in medication or dose within the last month
- Use of mouthwash within the last week
- Use of lozenges or chewing gum with 500 mg or more of xylitol on a habitual basis
- History of gastrointestinal disease
Key Trial Info
Start Date :
March 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2013
Estimated Enrollment :
7 Patients enrolled
Trial Details
Trial ID
NCT01823445
Start Date
March 1 2013
End Date
August 1 2013
Last Update
December 3 2013
Active Locations (1)
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1
University of Washington, School of Dentistry, Regional Clinical Dental Research Center
Seattle, Washington, United States, 98195