Status:
UNKNOWN
Spine Stereotactic Body Radiation Therapy for Metastatic Epidural Spinal Cord Compression
Lead Sponsor:
Samsung Medical Center
Collaborating Sponsors:
Seoul National University Hospital
Gachon University Gil Medical Center
Conditions:
Spinal Cord Compression
Eligibility:
All Genders
20+ years
Phase:
PHASE2
Brief Summary
Metastatic epidural spinal cord compression (MESCC) is a frequent oncologic emergency that requires to be treated promptly. Although direct decompressive surgery is the most effective treatment, surge...
Detailed Description
The definition of metastatic epidural spinal cord compression (MESCC) * MESCC is defined as both an evidence of cord compression by radiologic evaluation and a manifestation of clinical feature at th...
Eligibility Criteria
Inclusion
- MESCC is present.
- Localized spine metastases (C1 to L5 level); Maximum 3 separate sites and maximum 2 contiguous vertebral bodies
- Performance state before the occurrence of neurologic symptoms : Eastern Cooperative Oncology Group 0-2
- Age ≥20
- MRI within 2 weeks is mandatory
- Paraspinal mass \< 5cm in maximum dimension
- Inoperable patients - refused or medically unfit for decompression surgery
- life expectancy \> 3 months
Exclusion
- Retropulsed bony fragment causing cord compression
- Paraplegia ≥ 48 hours
- Histology preferred to perform the chemotherapy as the first option (e.g. lymphoma, myeloma)
Key Trial Info
Start Date :
October 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2015
Estimated Enrollment :
43 Patients enrolled
Trial Details
Trial ID
NCT01826058
Start Date
October 1 2012
End Date
August 1 2015
Last Update
December 2 2014
Active Locations (1)
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1
Samsung Medical Center
Seoul, South Korea, 135-710