Status:
COMPLETED
Prediction of Postoperative Pain by Measuring Nociception at the End of Surgery
Lead Sponsor:
Benno Rehberg-Klug
Collaborating Sponsors:
University Hospital, Geneva
Conditions:
Acute Postoperative Pain
Eligibility:
FEMALE
18+ years
Brief Summary
There is a large variability of postoperative pain intensity and of the drug doses necessary to alleviate this pain. The investigators hypothesis is that a measurement of nociception at the end of sur...
Detailed Description
Acute postoperative pain needs to be alleviated quickly to avoid sensitization in the postoperative period, since sensitization can lead to pain chronification. Severe acute postoperative pain is the ...
Eligibility Criteria
Inclusion
- American Society of Anesthesiology (ASA) physical status less than 3
- Able to read and understand the information sheet and to sign and date the consent form
- Being scheduled for elective gynaecological intraperitoneal surgery (laparoscopy, laparoscopic hysterectomy, vaginal hysterectomy, abdominal hysterectomy) under general anesthesia
- Age\>18
Exclusion
- Regional anesthesia (epidural analgesia, multi-orifice wound catheter, or transversus abdominis plane block) used for postoperative analgesia
- Surgery performed under regional anesthesia
- Contraindication to a general anesthesia using propofol and sufentanil (e.g. necessity for rapid sequence induction)
- BMI \>35 (limit of the equations used in the target controlled infusion device)
- Severe renal insufficiency precluding use of morphine (GFR\<30 ml/min)
Key Trial Info
Start Date :
June 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2017
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT01828424
Start Date
June 1 2013
End Date
June 1 2017
Last Update
September 6 2019
Active Locations (1)
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1
Hôpitaux Universitaires de Genève
Geneva, Switzerland, 1211