Status:

UNKNOWN

Study of New RIC Regimen of BuFlu in Older and/or Intolerable Patients

Lead Sponsor:

Peking University People's Hospital

Conditions:

Leukemia

Myelodysplastic Syndrome

Eligibility:

All Genders

55-70 years

Brief Summary

The purpose of this study is to determine whether the new RIC regimen, containing of low dose of Bu (9.6mg/kg)and fludarabine without ATG, is suitable and effective in treating aged and/or intolerable...

Eligibility Criteria

Inclusion

  • diagnosed of hematologic malignant disease
  • will undergo HLA matced HSCT
  • age \>=55years
  • \<55year and intolerable to standard myeloablative conditioning

Exclusion

  • KPS status \<70
  • cardiac EF\<50%
  • creatine clearance \<50 ml/min
  • ALT more than 10 times of upper normal limit

Key Trial Info

Start Date :

February 1 2013

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT01828619

Start Date

February 1 2013

Last Update

April 10 2013

Active Locations (1)

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1

Peking University People's Hospital

Beijing, China, 100044