Status:
COMPLETED
Whole Body Diffusion Weighted Magnetic Resonance Imaging (DW-MRI) in Multiple Myeloma
Lead Sponsor:
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Conditions:
Multiple Myeloma
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Bone disease in multiple myeloma (MM) is routinely assessed by skeletal X-ray (XR) and magnetic resonance of the spine (S-MRI). Diffusion-weighted MRI (DW-MRI) is a functional MRI that detects water d...
Detailed Description
PROTOCOL SYNOPSIS - Study Type Monocentric prospective clinical trial Study Object Comparison of Whole Body Diffusion Weighted Magnetic Resonance Imaging (DW-MRI) with skeletal X-Ray and MRI of the s...
Eligibility Criteria
Inclusion
- •
- .Age ≥18 years , \< 80 years
- Stage I-III (Durie-Salmon) symptomatic MM at the start of first-line treatment or at relapse after disease response (CR or PR) lasting at least 6 months
- Stage I (Durie-Salmon) asymptomatic MM at diagnosis not requiring treatment (substudy for assessment of exploratory objectives)
- Written informed consent
Exclusion
- Pregnancy or lactation
- Active secondary malignancy
- Type I hypersensitivity or anaphylactic reactions to Gadolinum contrast agent
- Mental disorders including claustrophobia (ICD 10, F40.2)
- Electronically, magnetically and mechanically activated implants
- Ferromagnetic or electrically operated active devices like automatic cardioverter defibrillators
- Cardiac pacemakers
- Metallic splinters in the eye
- Ferromagnetic haemostatic clips in the central nervous system (CNS) or in the body
- Cochlear implants or stapedial implants
- Insulin pumps and nerve stimulators
- Prosthetic hearth valves
Key Trial Info
Start Date :
July 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2012
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT01829412
Start Date
July 1 2008
End Date
July 1 2012
Last Update
April 11 2013
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.