Status:
ACTIVE_NOT_RECRUITING
DIGItal Cohort Osteoarthritis Design
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Arthrosis of Hand
Eligibility:
All Genders
35+ years
Phase:
NA
Brief Summary
Introduction Osteoarthritis is a chronic disease characterized by a progressive degradation of articular cartilage. Hand OA involves symptomatically more than 1 million of subjects in France (i.e., pa...
Detailed Description
Primary objective To investigate in hand OA patients predictive clinical, biological, genetic and imaging factors of clinical aggravation after 6 years of follow-up. Secondary objectives To investiga...
Eligibility Criteria
Inclusion
- Patients above 35-years old, having hand OA according to one of the following definitions:
- symptomatic hand OA fulfilling ACR criteria on at least 2 joints among proximal interphalangeal, distal interphalangeal joints or 1st interphalangeal joint with Kellgren-Lawrence \> 2
- symptomatic thumb base OA with Kellgren-Lawrence \> 2
Exclusion
- Inflammatory rheumatic destructive disorders (psoriatic arthritis, rheumatoid arthritis)
- Polyarthritis related to gout or chondrocalcinosis involving hand
- Secondary hand OA related to infection or traumatism
- Secondary OA related to genetic dysplasia
- Pregnancy and feeding
Key Trial Info
Start Date :
April 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2027
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT01831570
Start Date
April 1 2013
End Date
June 1 2027
Last Update
April 2 2025
Active Locations (1)
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1
Service de Rhumatologie - Hôpital Saint-Antoine
Paris, France, 75012