Status:
UNKNOWN
Effect of L-Thyroxine on Lipid Profiles and Atherosclerosis in Subclinical Hypothyroidism
Lead Sponsor:
Shandong Provincial Hospital
Conditions:
Hypothyroidism
Thyroid Diseases
Eligibility:
All Genders
18-60 years
Phase:
PHASE4
Brief Summary
Subclinical hypothyroidism (SCH) is a common condition affecting 3-10% of the general population, especially in women older than 50 years old. It is controversial whether SCH can lead to increased ris...
Eligibility Criteria
Inclusion
- Male and female aged of 18 to 60 years old;
- Diagnosis was subclinical hypothyroidism(elevated serum thyroid-stimulating hormone levels with normal serum free T4 levels measured at least two times with a three-month interval);
- untreated.
Exclusion
- Pregnancy or lactation women;
- Presence of pituitary/hypothalamic disorders, diabetes mellitus or other endocrinal and metabolic disorders;
- Presence of psychological or physical disabilities,acute infection, cerebrovascular or cardiovascular disease, chronic respiratory disease and other illnesses known to alter lipid metabolism;
- Taking lipid-lowering agents and other drugs that known to influence thyroid function, blood pressure, heart function or bile acids;
- Obviously poor compliance.
Key Trial Info
Start Date :
April 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2022
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT01831869
Start Date
April 1 2013
End Date
April 1 2022
Last Update
September 12 2018
Active Locations (1)
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1
Shandong Provincial Hospital
Jinan, Shandong, China, 250021