Status:

UNKNOWN

Impact of Blood Glucose at the First Trimester of Pregnant Women With Gestational Diabetes on Maternal and Fetal Outcomes and Metabolic Disorders: a Multi-central Prospective Cohort Study

Lead Sponsor:

First Affiliated Hospital, Sun Yat-Sen University

Conditions:

Gestational Diabetes

Eligibility:

FEMALE

18-60 years

Phase:

NA

Brief Summary

The study is to investigate the impact of blood glucose management at the first trimester of pregnant women with gestational diabetes on the maternal and fetal outcomes and metabolic disorder.

Detailed Description

Gestational diabetes(GDM) is the glucose metabolic disorder that first diagnosed during pregnancy. With the development of social economy and the improvement of life, the incidence of GDM increases to...

Eligibility Criteria

Inclusion

  • regular antenatal examination from the first trimester;
  • accurate left mentoposterior(LMP) verified by ultrasonography(USG);
  • fasting blood glucose level between 5.1 mmol/L and 7.0 mmol/L.

Exclusion

  • younger than 18 years old;
  • do not give birth in the research centers above;
  • LMP is undefined and lack of USG during 6-14 gestational weeks;
  • multiple pregnancy;
  • non-natural pregnancy(including intrauterine insemination(IUI), in-vitro fertilization and embryo transfer(IVF-ET), etc);
  • diagnosed DM before pregnancy;
  • with hepatitis B virus, hepatitis C virus, HIV infection;
  • taking drugs including glucocorticoid, diuretic, angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker(ACEI/ARB), etc.
  • complicated with diseases that affect glucose metabolism such as hyperthyroidism and so on.

Key Trial Info

Start Date :

June 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2021

Estimated Enrollment :

3 Patients enrolled

Trial Details

Trial ID

NCT01833559

Start Date

June 1 2012

End Date

August 1 2021

Last Update

March 18 2014

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Gynecology and obstetrics department of the 1st affiliated hospital of Sun Yat-sen University

Guangzhou, Guangdong, China, 510080