Status:

COMPLETED

Kinetic of Cytokines Decrease and Hodgkin Lymphoma Prognostic

Lead Sponsor:

Centre Henri Becquerel

Conditions:

Hodgkin's Disease

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

More than 90% of patients with Hodgkin lymphoma (HL) can recover thanks to conventional polychemotherapy regimens - ABVD or BEACOPP - with or without radiotherapy. Nevertheless, some patients relapse ...

Detailed Description

To evaluate the decrease of cytokines concentration with a prognostic value as markers of response, the dosage of TARC, IL-6, IL1-RA, sCD30 and TNFR1 will be performed during treatment at :diagnosis, ...

Eligibility Criteria

Inclusion

  • Hodgkin Lymphoma diagnosis
  • I-II or III-IV Stages
  • untreated Patient (including corticosteroids)
  • Patient treated and followed exclusively in center Henri Becquerel
  • Informed Consent signed

Exclusion

  • psychological, social or family conditions not allowing a suitable follow-up for study
  • Mental deficiency not allowing the good understanding of study procedures
  • positive HIV serology
  • positive B or C Hepatitis serology
  • Pregnant or lactating
  • Patient registered with a social security scheme or in an equivalent situation
  • Patient in a period of exclusion on another biomedical study.

Key Trial Info

Start Date :

April 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2016

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT01833884

Start Date

April 1 2010

End Date

June 1 2016

Last Update

July 21 2017

Active Locations (1)

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1

Centre Henri Becquerel

Rouen, France, 76000