Status:
UNKNOWN
Molecular Mechanism of POP Kidney Yin Deficiency Syndrome From the Interventional Effects of CLCF1
Lead Sponsor:
Fujian Academy of Traditional Chinese Medicine
Conditions:
Postmenopausal Osteoporosis
Eligibility:
FEMALE
45-75 years
Phase:
PHASE2
Brief Summary
This study use RT-PCR and Western Blot technique to detect the expression of CLCF1 mRNA and protein in POP Kidney Yin deficiency group and healthy group to verify the relevance between CLCF1 and POP t...
Eligibility Criteria
Inclusion
- The Participants who volunteer to be test subjects, and can accept experimental drugs, and promise to finish the course should sign the informed consent.
- Female ages 45 to 75 had gone through natural menopause before two years
- In accordance with the western medicine diagnostic criteria of osteoporosis and belong to kidney Yin deficiency syndrome differentiation of traditional Chinese medicine certificate;
- In accordance with the western medicine diagnostic criteria;
- In accordance with TCM diagnostic methods; .If any of the above answers are no, The subjects couldn't in the study.
Exclusion
- Do not accord with standard of the western medicine diagnosis and TCM diagnostic methods
- Age: \<44 and \> 76 years old;
- With hyperparathyroidism, osteomalacia, rheumatoid arthritis, multiple myeloma and other serious complications such as secondary osteoporosis; Late or deformity, disability, loss of labor;
- With cardiovascular, cerebrovascular, liver, kidney and hematopoietic system and other serious primary diseases;
- Psychosis or alzheimer's patients;
- Nearly three months, the use of hormone replacement therapy (HRT) and taking calcitonin, nearly six months has used double phosphonic acid salt for 15 days, etc.;
- This medicine allergic constitution or composition of known to have allergies;
- In a critical condition, It's difficult to make exact evaluators to efficacy and safety of the new drugs;
Key Trial Info
Start Date :
January 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT01834105
Start Date
January 1 2012
Last Update
April 18 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Fujian Institute of Trational Chiness Medicine
Fuzhou, Fujian, China, 3530003