Status:

COMPLETED

Imaging of Peritoneal Carcinomatosis From Ovarian Carcinoma Patients

Lead Sponsor:

Jules Bordet Institute

Conditions:

Ovarian Cancer

Peritoneal Carcinomatosis

Eligibility:

FEMALE

18-65 years

Phase:

PHASE1

PHASE2

Brief Summary

The purpose of this study is to determine if NIF fluorescent imaging is an effective approach to detect the gross ovarian tumoral tissues and peritoneal implants in Ovarian cancer patients.

Detailed Description

Primary objective: Evaluation of the ability of NIR imaging to image and to detect the " viable " gross tumoral mass and/or peritoneal metastatic " implants " in women operated for ovarian carcinoma ...

Eligibility Criteria

Inclusion

  • Patients (either newly diagnosed, or relapsing) with histo-pathological diagnosis of ovarian carcinoma and peritoneal carcinomatosis who are candidate for "open" surgery, either after neo-adjuvant chemotherapy (80-90% of the cases), or in "first intent".
  • Informed consent form signed.

Exclusion

  • Age less than18 years old.
  • Inability to give informed consent.
  • History of allergy or hypersensitivity against the investigational product (its active substance or ingredients), to iodine or to shellfish.
  • Apparent hyperthyroidism, autonomous thyroid adenoma, unifocal, multifocal or disseminated autonomies of the thyroid gland.
  • Documented coronary disease.
  • Advanced renal impairment (creatinine \> 1,5mg/dl).

Key Trial Info

Start Date :

March 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2014

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT01834469

Start Date

March 1 2013

End Date

October 1 2014

Last Update

October 15 2014

Active Locations (1)

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Jules Bordet Institute

Brussels, Belgium, B-1000