Status:
COMPLETED
Modified Atkins Diet Plus KetoCal for Adult Epilepsy
Lead Sponsor:
Johns Hopkins University
Collaborating Sponsors:
Nutricia Liverpool
Conditions:
Epilepsy
Seizure
Eligibility:
All Genders
18-100 years
Phase:
NA
Brief Summary
The modified Atkins diet (MAD) has been shown to be effective in treating children and adults with medically resistant seizures. A recent study in children showed that the use of KetoCal® once per day...
Eligibility Criteria
Inclusion
- Adults ages \>17 years.
- At least weekly seizures (or 4 per month). All seizure types allowed.
- Tried at least two anticonvulsants.
Exclusion
- Unwilling to restrict carbohydrates
- Significantly underweight (Body Mass Index \<18.5)
- Prior use of the modified Atkins diet for ≥ 2 days
- Prior use of KetoCal® at any time for any duration
- Use of the ketogenic diet within the past year
- Kidney disease
- History of hypercholesterolemia (total cholesterol \> 300 mg/dl) or hypertriglyceridemia (triglycerides \> 200 mg/dl)
- Metabolic or mitochondrial disorder
- Pregnancy or breastfeeding
- Lactose intolerance or milk allergy
- Aversion to liquids or inability to eat solid food
Key Trial Info
Start Date :
March 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2017
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT01834482
Start Date
March 1 2013
End Date
September 1 2017
Last Update
August 31 2018
Active Locations (1)
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1
Johns Hopkins University
Baltimore, Maryland, United States, 21287