Status:

UNKNOWN

A Randomized Comparative Effectiveness Research Trial of Three Treatments for COPD Patients

Lead Sponsor:

Henan University of Traditional Chinese Medicine

Conditions:

Pulmonary Disease, Chronic Obstructive

Eligibility:

All Genders

18-80 years

Phase:

PHASE3

Brief Summary

The aim of this study is to compare the effectiveness and economic evaluation of three treatments for Chronic Obstructive Pulmonary Disease (COPD) patients: one, conventional medicine based on 2011 Gl...

Detailed Description

COPD affects millions worldwide. The high prevalence, morbidity, mortality and economic burdens of COPD are increasing steadily. Although many therapies exist and are being developed to relieve sympto...

Eligibility Criteria

Inclusion

  • A confirmed diagnosis of mild to very severe COPD.
  • medically stable
  • Age between 18 and 80 years.
  • Syndrome differentiation belongs to Syndrome of lung-qi deficiency, Syndrome of deficiency of pulmonic-splenic qi, Syndrome of insufficiency of qi of the lung and kidney, syndrome of insufficiency of qi and yin of the lung and kidney.
  • Without participations in other interventional trials in the previous one month.
  • With the informed consent signed.

Exclusion

  • Pregnant or breast-feeding women.
  • Any psychiatric condition rendering the patient unable to understand the nature, scope and possible consequences of the study .
  • Malignancy for which patient has undergone resection, radiation therapy or chemotherapy within the last 5 years.
  • Current respiratory disorders other than COPD (e.g., bronchiectasis, tuberculosis, lung fibrosis, pulmonary thromboembolic).
  • Complicated with heart failure (NYHA Class III or IV),or myocardial infarction within six months ,or unstable hemodynamics.
  • Complicated with serious hepatic and renal diseases (liver cirrhosis, portal hypertension, bleeding of varicose veins, dialysis, or renal transplantation).
  • Participating in other trials or allergic to the used medicine.

Key Trial Info

Start Date :

May 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2015

Estimated Enrollment :

360 Patients enrolled

Trial Details

Trial ID

NCT01836016

Start Date

May 1 2013

End Date

May 1 2015

Last Update

April 19 2013

Active Locations (1)

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1

The First Affiliated Hospital of Henan University of Traditional Chinese Medicine

Zhengzhou, Henan, China, 450000