Status:

UNKNOWN

A Study of Raltitrexed Plus Docetaxel Versus Docetaxel as Second-line Chemotherapy in Subjects With Gastric Cancer

Lead Sponsor:

Hebei Tumor Hospital

Conditions:

Gastric Cancer

Eligibility:

All Genders

18-75 years

Phase:

PHASE2

Brief Summary

A study of Raltitrexed plus Docetaxel versus Docetaxel as second-line chemotherapy in subjects with Gastric Cancer.The purpose of this study is to compare the activity of Raltitrexed plus Docetaxel ve...

Eligibility Criteria

Inclusion

  • Signed informed consent form
  • Performance Status- Eastern Cooperative Oncology Group (ECOG) 0-2;
  • Histologically or cytologically confirmed gastric cancer;
  • The first-line chemotherapy failure (required containing 5-fluorouracil)
  • At least have one measurable disease(according to RECIST, Response Evaluation Criteria in Solid Tumors )
  • Life expectancy of at least 3 months;

Exclusion

  • Received any prior treatment including Raltitrexed;
  • Active or uncontrolled infection;
  • Concurrent treatment with an investigational agent or participation in another therapeutic clinical trial;
  • Pregnant or lactating women.

Key Trial Info

Start Date :

April 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2017

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT01836120

Start Date

April 1 2013

End Date

June 1 2017

Last Update

April 19 2013

Active Locations (1)

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Hebei Tumor Hospital

Shijiazhuang, Hebei, China, 050011