Status:

COMPLETED

Selection of Potential Predictors of Worsening Heart Failure

Lead Sponsor:

Biotronik SE & Co. KG

Conditions:

Heart Failure

Eligibility:

All Genders

18+ years

Brief Summary

Multicentre study with the objective to correlate heart failure hospitalizations and deaths with Home Monitoring data in ICD/CRT-D recipients, in order to identify the combination of Home Monitoring d...

Detailed Description

Home Monitoring remotely provides continuous trends of potential HF-related variables with a sampling interval of 24 hours. Although the predictive value of individual variables may be limited, a prop...

Eligibility Criteria

Inclusion

  • Left Ventricular Ejection Fraction (LVEF) ≤ 35%
  • NYHA Class II or III Heart Failure
  • Men and women 18 years of age or older
  • Understand the nature of the procedure
  • Give written informed consent

Exclusion

  • No indication or contraindication for ICD or CRT-D therapy
  • Permanent AF
  • NYHA Class IV Heart Failure
  • Subjects with irreversible brain damage from preexisting cerebral disease;
  • Subjects with acutely decompensated heart failure
  • Expected heart transplantation within next six months or planned cardiac surgery within next 3 months
  • Have a life expectancy of less than six months
  • Presence of any disease, other than the subject's cardiac disease associated with a reduced likelihood of survival for the duration of the trial, (e.g. cancer)
  • Unstable geographical residence (unable to anticipate to be resident in the area of the referring participating centre during the study period) and/or GSM-free residence
  • Subjects who were not been implanted with ICD or CRT-D devices compatible with HM transmissions
  • Age \<18 years
  • Pregnancy

Key Trial Info

Start Date :

May 1 2012

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 28 2017

Estimated Enrollment :

922 Patients enrolled

Trial Details

Trial ID

NCT01836510

Start Date

May 1 2012

End Date

February 28 2017

Last Update

January 18 2020

Active Locations (34)

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Page 1 of 9 (34 locations)

1

Cliniche Humanitas Gavazzeni

Bergamo, Italy

2

Spedali Civili

Brescia, Italy

3

Di Summa Hospital

Brindisi, Italy

4

Fondazione Giovanni Paolo II

Campobasso, Italy