Status:

COMPLETED

An Efficacy and Safety Study of BG00012 (Dimethyl Fumarate) in Asian Subjects With Relapsing Remitting Multiple Sclerosis (RRMS)

Lead Sponsor:

Biogen

Conditions:

Relapsing-Remitting Multiple Sclerosis

Multiple Sclerosis

Eligibility:

All Genders

18-55 years

Phase:

PHASE3

Brief Summary

This is a multicenter study conducted in 2 parts: The primary objective in Part I of this study is to determine the efficacy of BG00012 (dimethyl fumarate, DMF) on inflammatory brain magnetic resonan...

Eligibility Criteria

Inclusion

  • Key
  • Inclusion Criteria for Part I:
  • Must have a diagnosis of Relapsing-Remitting Multiple Sclerosis (RRMS).
  • Must have a baseline Expanded Disability Status Scale (EDSS) score between 0.0 and 5.0, inclusive.
  • Key Inclusion Criteria for Part II:
  • • Subjects who participated in and completed Part I per protocol.
  • Key

Exclusion

  • Other chronic disease of the immune system, malignancies, acute urologic, pulmonary, gastrointestinal disease.
  • Pregnant or nursing women.
  • NOTE: Other protocol-defined inclusion/exclusion criteria may apply.

Key Trial Info

Start Date :

March 28 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 4 2018

Estimated Enrollment :

225 Patients enrolled

Trial Details

Trial ID

NCT01838668

Start Date

March 28 2013

End Date

September 4 2018

Last Update

November 20 2018

Active Locations (54)

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Page 1 of 14 (54 locations)

1

Fakultni nemocnice u sv. Anny v Brne

Brno, Czechia, 656 91

2

Neurospol, s.r.o.

Havířov, Czechia, 736 00

3

Fakultni nemocnice Hradec Kralove

Hradec Králové, Czechia, 500 05

4

Privatni ordinace - neurologie

Hradec Králové, Czechia, 50003