Status:
COMPLETED
Effect of Combination Dexmedetomidine Added to Fentanyl-based Intravenous Patient-controlled Analgesia on Nausea Vomiting in Highly Susceptible Patients Undergoing Lumbar Spinal Surgery: Prospective Double Blinded Randomized Controlled Trial
Lead Sponsor:
Yonsei University
Conditions:
PONV
Eligibility:
FEMALE
20-65 years
Phase:
NA
Brief Summary
The aim of this study is to test the hypothesis that addition of dexmedetomidine to fentanyl-based intravenous patient controlled analgesia (PCA) reduces requirement of fentanyl bolus and consequent p...
Eligibility Criteria
Inclusion
- 1\. female, non-smoking patient who are 20-65 of age scheduled for elective lumbar spine surgery
Exclusion
- Bradycardia on EKG (45bpm)
- Atrioventricular conduction disorder
- Uncontrolled hypertension
- angina history
- obesity (BMI ≥ 30 kg/m2)
- Preoperative administration of opioid
- Preoperative administration of antiemetics
- Gastrointestinal disorder history
- Hepatic or renal disease
- Pregnant 11. Foreigner
Key Trial Info
Start Date :
September 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2013
Estimated Enrollment :
108 Patients enrolled
Trial Details
Trial ID
NCT01840254
Start Date
September 1 2012
End Date
September 1 2013
Last Update
February 7 2014
Active Locations (1)
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1
Yonsei University College of Medicine
Seoul, Seoul, South Korea, 120-752