Status:
TERMINATED
Validation of [18F]FES for Imaging of Brain Estrogen Receptors
Lead Sponsor:
University Medical Center Groningen
Conditions:
Psychiatric/Mood Disorder | Patient
Estrogen Receptor Levels
Eligibility:
FEMALE
18-65 years
Phase:
NA
Brief Summary
Validation of \[18F\]-FES for imaging of estrogen receptors in the brain The primary objective of the study is to determine if \[18F\]-FES Positron Emission Tomography (PET) can be used to quantify t...
Detailed Description
Estrogens are the primary female sex hormones that play a major role in the development and maintenance of secondary sexual functions. In addition, estrogens play an important role in cardiovascular, ...
Eligibility Criteria
Inclusion
- Female
- Age \> 18 years
- For postmenopausal women: at least 1 year after menopause
- For premenopausal women: a regular menstruation
- Signed written informed consent
Exclusion
- Use of estrogen receptor ligands, such as tamoxifen or fulvestrant
- History of ER-positive malignancies or breast cancer
- Use of any contraceptive drugs (pill, injections or implanted)
- For postmenopausal women: (history of) estrogen replacement therapy
- Pregnancy
- History of removal of the ovaries and/or the uterus
- Current systemic diseases
- Major metabolic diseases (e.g. diabetes, hyper- or hypothyroidism)
- Somatic, organic or neurological disorders
- Recent participation in a scientific research study (\<1 year) involving radiation
- Claustrophobia
- Presence of materials in the body that can be magnetized, like: pacemaker, metallic implants/prostheses, metal fragments, shunts, artificial heart valves, vascular clips, fixed hearing aid, tattoos containing metal, hair implants, artificial dentures
Key Trial Info
Start Date :
November 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2016
Estimated Enrollment :
3 Patients enrolled
Trial Details
Trial ID
NCT01842217
Start Date
November 1 2013
End Date
January 1 2016
Last Update
April 18 2024
Active Locations (1)
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1
University Medical Centre Groningen
Groningen, Netherlands, 9700RB