Status:
COMPLETED
Image-Guided Adaptive Radiotherapy for in Detecting Tumors During Treatment in Patients With Head and Neck Cancer
Lead Sponsor:
Virginia Commonwealth University
Conditions:
Head and Neck Cancer
Eligibility:
All Genders
21+ years
Phase:
NA
Brief Summary
This clinical trial studies image-guided adaptive radiotherapy in detecting tumors during treatment in patients with head and neck cancer. Image-guided adaptive radiotherapy uses high quality imaging ...
Detailed Description
I. To conduct a clinical imaging study utilizing three novel in-room imaging systems: Oblique Brainlab ExacTrac images, Orthogonal Varian kilovoltage (kV) On-board Imaging (OBI) image, and Varian cone...
Eligibility Criteria
Inclusion
- Histologic or cytologic confirmation of head and neck malignancy
- Patients who will be treated with definitive radiation therapy or concurrent chemoradiation therapy
- Gross tumor volume (GTV) must be visible on CT
- All patients must be informed of the investigational nature of this study and must give written informed consent in accordance with institutional and federal guidelines
Exclusion
- Pregnant or nursing women may not participate; women of reproductive potential must be offered a pre-treatment pregnancy test and informed of the need to practice an effective contraceptive method
- Prior treatment with radiation therapy to the head and neck
- Serum creatinine \> 1.5 and/or
- Blood urea nitrogen \[BUN\] \> 25
- Treatment with any prior chemotherapy or surgery (excluding diagnostic biopsy) for this malignancy
- Patients with known syndromes expected to alter radiosensitivity (e.g. ataxia-telangiectasia, scleroderma, lupus, human immunodeficiency virus \[HIV\]/acquired immunodeficiency deficiency syndrome \[AIDS\]) may not participate
Key Trial Info
Start Date :
January 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2015
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT01843673
Start Date
January 1 2009
End Date
January 1 2015
Last Update
July 6 2016
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Virginia Commonwealth University, Massey Cancer Center
Richmond, Virginia, United States, 23298