Status:

COMPLETED

Frailty Assessment Before Cardiac Surgery & Transcatheter Interventions

Lead Sponsor:

Jewish General Hospital

Collaborating Sponsors:

Beth Israel Deaconess Medical Center

Brigham and Women's Hospital

Conditions:

Aortic Stenosis

Cardiac Valve Replacement Complication

Eligibility:

All Genders

70+ years

Brief Summary

Frailty is a state of decreased physiologic reserves and vulnerability to stressors. Several tools exist to measure frailty, some based on physical tests and others on questionnaires, yet there is no ...

Eligibility Criteria

Inclusion

  • Age ≥70 years (a site-specific substudy at the JGH will enroll ages ≥21 years)
  • Severe AS
  • Referred for surgical or transcatheter AVR (with or without concomitant revascularization)
  • Signed informed consent

Exclusion

  • Emergency surgery
  • Clinical instability: decompensated heart failure, active ischemia, unstable vital signs
  • Severe neuropsychiatric impairment
  • Not English or French speaking
  • Replacement of \>1 valve or aortic surgery

Key Trial Info

Start Date :

January 1 2012

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 1 2016

Estimated Enrollment :

800 Patients enrolled

Trial Details

Trial ID

NCT01845207

Start Date

January 1 2012

End Date

March 1 2016

Last Update

August 31 2016

Active Locations (14)

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Page 1 of 4 (14 locations)

1

Massachusetts General Hospital

Boston, Massachusetts, United States, 02114

2

Brigham & Women's Hospital

Boston, Massachusetts, United States, 02115

3

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States, 02215

4

Duke University Medical Center

Durham, North Carolina, United States, 27705