Status:
UNKNOWN
Feasibility of Contact Force Catheter Mapping and Ablation in Epicardial and Endocardial Ventricular Tachycardias
Lead Sponsor:
Federal University of São Paulo
Conditions:
Ventricular Tachycardia
Sudden Death
Eligibility:
All Genders
18-80 years
Brief Summary
Ventricular tachycardia is one of the commonest cause of sudden death in chronic chagas disease. As most ventricular tachycardias originate from scar in patients with heart disease, catheter ablation ...
Eligibility Criteria
Inclusion
- individuals aged between 18 and 80 years old
- life expectancy greater than 1 year
- positive reaction in at least two different serologic techniques for Chagas disease (ELISA, indirect hemagglutination or indirect immunofluorescence)
- symptomatic recurrent monomorphic ventricular tachycardia (recorded by holter, electrocardiogram or looper)
- prior to implantable cardioverter defibrillator implantation in patients with ventricular tachycardia as an attempt to prevent shoks
- patients in "electrical storm", defined as three or more episodes of ventricular tachycardia in 24h. Each episode must demand a medical intervention.
- monomorphic ventricular tachycardia induced during electrical physiological study in patients with syncope of unexplained cause
Exclusion
- claustrophobia
- creatinine clearance inferior to 30ml/min/m2 (clearance between 30ml/min/m2 and 60ml/min/m2 will be analyzed individually)
- thrombus in the left ventricle
- pregnancy
- heart failure NYHA IV
- allergy to iodinated contrast or gadolinium
- patients with implantable devices (pacemakers, implantable defibrillators and similar)
- coagulopathy (INR \> 1,5 or aPTT 2x normal values)
- platelet count inferior to 100.000
Key Trial Info
Start Date :
June 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 1 2015
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT01847378
Start Date
June 1 2013
End Date
August 1 2015
Last Update
October 21 2014
Active Locations (3)
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1
Federal University of São Paulo, São Paulo Hospital
São Paulo, São Paulo, Brazil, 04024-002
2
Federal University of São Paulo
São Paulo, São Paulo, Brazil, 04024-002
3
Federal University of São Paulo
São Paulo, São Paulo, Brazil, SP