Status:
COMPLETED
Magnetic Resonance Diagnostics of Diabetic Peripheral Neuropathy
Lead Sponsor:
Aarhus University Hospital
Collaborating Sponsors:
University of Southern Denmark
Conditions:
Diabetes Mellitus, Type 1
Diabetes Mellitus, Type 2
Eligibility:
All Genders
18-90 years
Brief Summary
This project aims to develop high field MR techniques to detect nerve lesions in diabetic patients. The MRI findings will be compared to results from conventional evaluations and nerve conduction stud...
Detailed Description
Background Diabetes mellitus is a very frequent disorder with an estimated prevalence of 275,000 patients in Denmark. Diabetic peripheral neuropathy (DPN) is a late complication which often remains u...
Eligibility Criteria
Inclusion
- Clinical diagnosis of type 1 diabetes, without neuropathy
- Clinical diagnosis of type 2 diabetes, without neuropathy
- Clinical diagnosis of type 1 diabetes, with neuropathy
- Clinical diagnosis of type 2 diabetes, with neuropathy
- Clinical diagnosis of hereditary axonal neuropathy
- Clinical diagnosis of hereditary demyelinised neuropathy
- Healthy controls who do not use prescription drugs and are of normal weight (BMI between 20 and 30).
Exclusion
- The second cause of the neuropathy.
- Persons who are under 18.
- Inability to perform nerve conduction study or magnetic resonance imaging.
- Patients with liver disease, hypothyroidism, current or past alcohol abuse, rheumatological diseases and vasculitis.
- Silver Treatment, in diabetics with wounds.
Key Trial Info
Start Date :
May 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2016
Estimated Enrollment :
115 Patients enrolled
Trial Details
Trial ID
NCT01847937
Start Date
May 1 2013
End Date
September 1 2016
Last Update
February 3 2017
Active Locations (5)
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1
Department of Endocrinology and Internal Medicine
Aarhus, Aarhus, Denmark, 8000
2
Department of Neurology
Aarhus, Aarhus, Denmark, 8000
3
Department of Neurophysiology
Aarhus, Aarhus, Denmark, 8000
4
MR Centre
Aarhus, Aarhus, Denmark, 8000