Status:
COMPLETED
Temperature, Heart and Respiratory Rate Investigation Along With Variability Evaluation and Serum Biomarkers (THRRIVES)
Lead Sponsor:
Ottawa Hospital Research Institute
Collaborating Sponsors:
The Ottawa Hospital Academic Medical Association
Conditions:
Cancer
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to find a way of detecting infection earlier in patients receiving bone marrow transplant. This is accomplished by continuous individualized monitoring of heart rate, resp...
Detailed Description
In this prospective observational study, patients receiving bone marrow transplant are selected for continuous monitoring of heart rate, respiratory and temperate variability. Data is collected as per...
Eligibility Criteria
Inclusion
- An expected prolonged period of neutropenia
- Completing bone marrow;
- Allogeneic and/or autologous transplants OR
- Induction chemotherapy
Exclusion
- Inability to obtain written informed consent from patient or legally authorized representative
- Ongoing treatment for active infection (not prophylaxis)
- Preexisting severe cardiopulmonary disease (defined as an EF 40%, FEV 40%,or interstitial lung disease with pulmonary fibrosis)
- On betablockers or calcium channel blockers
- Preexisting arrhythmia
- Permanent pacemaker
- Inability to speak neither English nor French
Key Trial Info
Start Date :
March 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2022
Estimated Enrollment :
86 Patients enrolled
Trial Details
Trial ID
NCT01848912
Start Date
March 1 2013
End Date
May 1 2022
Last Update
November 21 2022
Active Locations (1)
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1
Bone Marrow Transplant Clinic,The Ottawa Hospital, General Campus
Ottawa, Ontario, Canada