Status:

COMPLETED

Providing Brain Control of Extracorporeal Devices to Patients With Quadriplegia

Lead Sponsor:

Richard A. Andersen, PhD

Collaborating Sponsors:

University of Southern California

Rancho Los Amigos National Rehabilitation Center

Conditions:

Tetraplegia

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

This research study is being done to develop a brain controlled medical device, called a brain-machine interface or BMI, that will provide people with a spinal cord injury some ability to control an e...

Eligibility Criteria

Inclusion

  • High cervical spinal lesion
  • Able to provide informed consent
  • Able to understand and comply with instructions in English
  • Able to communicate via speech
  • Surgical clearance
  • Life expectancy greater than 12 months
  • Live within 60 miles of study location and willing to travel up to 5 days per week
  • A regular caregiver to monitor the surgical site
  • Psychosocial support system

Exclusion

  • Presence of memory problems
  • intellectual impairment
  • Psychotic illness or chronic psychiatric disorder, including major depression
  • Poor visual acuity
  • Pregnancy
  • Active infection or unexplained fever
  • scalp lesions or skin breakdown
  • HIV or AIDS infection
  • Active cancer or chemotherapy
  • Diabetes
  • Autonomic dysreflexia
  • History of seizure
  • Implanted hydrocephalus shunt
  • Previous neurosurgical history affecting parietal lobe function
  • Medical conditions contraindicating surgery and chronic implantation of a medical device
  • Prior cranioplasty
  • Unable to undergo MRI or anticipated need for MRI during study
  • Nursing an infant or unwilling to bottle-feed infant
  • Chronic oral or intravenous use of steroids or immunosuppressive therapy
  • Suicidal ideation
  • Drug or alcohol dependence
  • Planning to become pregnant, or unwilling to use adequate birth control

Key Trial Info

Start Date :

February 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2019

Estimated Enrollment :

1 Patients enrolled

Trial Details

Trial ID

NCT01849822

Start Date

February 1 2013

End Date

January 1 2019

Last Update

April 30 2021

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Rancho Los Amigos National Rehabilitation Center

Downey, California, United States, 90242

2

University of Southern California

Los Angeles, California, United States, 90033

3

California Institute of Technology

Pasadena, California, United States, 91125