Status:

UNKNOWN

PREdicting Atrial Fibrillation or Flutter

Lead Sponsor:

Keesler Air Force Base Medical Center

Conditions:

Atrial Fibrillation

Atrial Flutter

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to determine, through continuous monitoring with a cardiac monitoring device placed under the skin, the incidence of atrial fibrillation or flutter (AF). The cardiac monit...

Detailed Description

Background: Atrial fibrillation and atrial flutter (AF) are common cardiac arrhythmias that confer a substantial stroke burden largely because the vast majority of AF is asymptomatic and identified af...

Eligibility Criteria

Inclusion

  • Patient meets the approved FDA indication to receive the ICM
  • Patient is suspected, based on demographics, to be at high risk of having AF, as determined by the clinical investigator
  • Patient has a CHA2DS2-VASc score ≥ 2 \[Note: stroke/TIA criterion as part of the CHA2DS2-VASc score for this trial is limited to either an ischemic stroke or TIA, which occurred more than one year prior to enrollment.\]
  • Patient is 18 years of age or older
  • Patient has a life expectancy of 18 months or more

Exclusion

  • Patient has a documented history of AF or atrial flutter
  • Patient has a symptom complex consistent with an arrhythmia (where an ICM may have an alternate indication for use)
  • Patient had an ischemic stroke or TIA within past year prior to enrollment
  • Patient has a history of a hemorrhagic stroke
  • Patient is currently implanted with a permanent pacemaker, insertable loop recorder, implantable defibrillator, cardiac resynchronization therapy device (pacemaker or defibrillator)
  • NYHA Class IV Heart Failure patient
  • Patient had heart surgery within previous 90 days prior to enrollment
  • Patient had an MI within the previous 90 days prior to enrollment
  • Patient is taking chronic immunosuppressant therapy
  • Patient is taking an anti-arrhythmic drug
  • Patient is contraindicated for long term anticoagulation medication
  • Patient is taking a long-term anticoagulation medication
  • Any concomitant condition which, in the opinion of the investigator, would not allow safe participation in the study (e.g., drug addiction, alcohol abuse, emotional / psychological diagnosis)
  • Patient is enrolled in another study that could confound the results of this study, without documented pre-approval from the principal investigator
  • Patient has a creatinine clearance \<30 ml/min or is on dialysis
  • Active pregnancy

Key Trial Info

Start Date :

May 1 2013

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2016

Estimated Enrollment :

360 Patients enrolled

Trial Details

Trial ID

NCT01851902

Start Date

May 1 2013

End Date

June 1 2016

Last Update

January 5 2016

Active Locations (1)

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Keesler Medical Center

Keesler Air Force Base, Mississippi, United States, 39534