Status:
COMPLETED
Respiratory Kinematics During Voluntary and Reflex Cough in Healthy Adults
Lead Sponsor:
University of Florida
Conditions:
Cough
Eligibility:
All Genders
18-80 years
Phase:
PHASE1
PHASE2
Brief Summary
Cough is a defensive behavior that involves three stages. A large inspiratory phase, a compression phase where the vocal folds close and subglottal pressure is developed, and an expiratory phase. Coug...
Detailed Description
As a participant, completion of this study will require the following: Investigators will first place cotton elastic bands around your chest and abdomen so that measures of chest wall and abdominal m...
Eligibility Criteria
Inclusion
- Healthy adults between the ages of 18-80 years.
- Ability to provide informed consent.
Exclusion
- No history of smoking within the last 5 years as this reduces the sensitivity to capsaicin
- No history of neurological disease (i.e. Parkinson's disease, stroke, traumatic brain injury, etc.)
- No known allergy to capsaicin
- No history of respiratory disease (i.e. asthma, chronic obstructive pulmonary disease, or respiratory infection within the last 5 weeks.)
Key Trial Info
Start Date :
May 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2014
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT01854268
Start Date
May 1 2013
End Date
May 1 2014
Last Update
February 9 2022
Active Locations (1)
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1
University of Florida, Dauer Hall
Gainesville, Florida, United States, 32611