Status:
COMPLETED
The Aim of This Investigation is to Compare the Influence of 0.9% Saline and Plasmalyte Solution on Acid-base Balance and Electrolytes in Healthy Patients Undergoing Major Spine Surgeries.
Lead Sponsor:
Yonsei University
Conditions:
Spinal Surgery
Eligibility:
All Genders
20-70 years
Phase:
NA
Brief Summary
Chloride-rich isotonic crystalloid solutions have been shown to exert electrolyte imbalance and metabolic acidosis in critically ill patients. The aim of this investigation is to compare the influence...
Eligibility Criteria
Inclusion
- 50 patients (aged 20-65) undergoing cervical or lumbar spine surgery who were diagnosed spinal stenosis involving more than tow spinal levels.
Exclusion
- ASA class III or IV
- pregnancy
- breast feeding
- lack of mental weakness(including disabled)
- using diuretics
- respiratory insufficiency
- metabolic acidosis or alkalosis
- coagulation disorder
- over hydtration
- renal failure or serum creatinine \> 1.4mg/dl
- anemia (Hemoglobin 9.0\<mg/dl)
- hypernatremia (Na \> 145mEq/L)
- Hyperkalemia (K\>5.5mEq/L)
- psychological medication or any drugs that influences renal clearance
Key Trial Info
Start Date :
March 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2013
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT01855542
Start Date
March 1 2012
End Date
January 1 2013
Last Update
May 16 2013
Active Locations (1)
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1
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine
Seoul, Seoul, South Korea, 120-752