Status:

COMPLETED

Comparative Study on the Effects of Epidural Dexmedetomidine on Heart Rate Variability During General Anesthesia in Patients Undergoing Gastrectomy

Lead Sponsor:

Yonsei University

Conditions:

Gastric Cancer

Eligibility:

All Genders

40-70 years

Phase:

NA

Brief Summary

The use of epidural dexmedetomidine decreases the anaesthetic requirements and improved postoperative pain. Dexmedetomidine is a potent and highly selective a2-adrenoceptor agonist and has sympatholyt...

Eligibility Criteria

Inclusion

  • Patients consented to spinal anesthesia were enrolled
  • Patients aged 40\~70 years olds undergoing gastrectomy
  • No contraindication of epidural analgesia
  • ASA class I and II
  • Patients consented to epidural anesthesia were enrolled

Exclusion

  • Patients with hypovolemia, coagulation disorders, local infection at the site of operation, history of headache, heart diseases, and history of allergy, chronic alcohol use or abuse, anemia, congenital heart diseases, bundle block, congestive heart failure or arrythmias
  • patients who had recently received sedative drugs or were under antidepressant treatment were not included in the study

Key Trial Info

Start Date :

February 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2013

Estimated Enrollment :

38 Patients enrolled

Trial Details

Trial ID

NCT01857141

Start Date

February 1 2012

End Date

August 1 2013

Last Update

February 5 2014

Active Locations (1)

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Department of Anesthesiology and Pain Medicine, and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea

Seoul, Seoul, South Korea, 120-752