Status:
COMPLETED
The Flashing Light-Induced Pupil Response (FLIPR) Glaucoma Study
Lead Sponsor:
Ohio State University
Conditions:
Glaucoma, Open-Angle
Eye Diseases
Eligibility:
All Genders
18+ years
Brief Summary
This study is designed to investigate whether the pupil response to slowly flashing colored lights is significantly altered in patients with glaucoma, as compared to a control group of subjects withou...
Detailed Description
The pupils inside the eyes constrict in response to light stimulation. Different classes of cells within the human retina initiate this response. Recent research suggests that one of the ganglion cell...
Eligibility Criteria
Inclusion
- 18+ years old
- Diagnosed with glaucoma of known severity (cases only)
- Have a refractive error between +4.00 and -8.00 sphere power, and no more than 3.00 diopters of astigmatism
- Best corrected visual acuity of 20/40 or better in each eye
- Have open anterior chamber angles
Exclusion
- Diagnosis of glaucoma of a type other than Primary Open Angle (cases only)
- History of having surgery or taking medications known to profoundly affect pupillary function or shape
- Visual Field defect (controls only)
- History of traumatic brain injury requiring hospitalization
- Pregnancy
- History of optic nerve disease other than glaucoma
- History of retinopathy
- History of unreactive pupils
- Presence of significant cataract
Key Trial Info
Start Date :
May 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2015
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT01857440
Start Date
May 1 2013
End Date
December 1 2015
Last Update
September 25 2017
Active Locations (2)
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1
OSU College of Optometry
Columbus, Ohio, United States, 42310
2
Havener Eye Institute
Columbus, Ohio, United States, 43212