Status:

WITHDRAWN

Internal Radiation Therapy in Treating Patients With Low-Risk Prostate Cancer

Lead Sponsor:

Jonsson Comprehensive Cancer Center

Conditions:

Adenocarcinoma of the Prostate

Recurrent Prostate Cancer

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

This phase II trial studies how well internal radiation therapy works in treating patients with low-risk prostate cancer. Internal radiation uses radioactive material placed directly into or near a tu...

Detailed Description

PRIMARY OBJECTIVES: I. To determine long term 5 year prostate specific cancer (PSA) biochemical control using the Phoenix definition of PSA nadir + 2 of targeted hemi-gland brachytherapy. SECONDARY ...

Eligibility Criteria

Inclusion

  • Histologically confirmed primary non-metastatic adenocarcinoma of the prostate
  • Unilateral prostate cancer as determined by prostate biopsy
  • Less than or equal to 3 positive biopsy cores
  • No biopsy core \>= 50% positive for cancer
  • Karnofsky performance status (KPS) \>= 70
  • At least a 12 core prostate biopsy; if this was not performed then it will be repeated here at University of California at Los Angeles (UCLA)
  • Artemis guided biopsy of any suspicious target lesions as identified on multiparametric (mp)-magnetic resonance imaging (MRI)
  • Clinical stage T1c or T2a
  • PSA \< 10 ng/ml
  • Gleason score 3+3=6

Exclusion

  • Patients who have previously received radiation therapy to the pelvis
  • Refusal to sign the informed consent
  • Patients who are participating in a concurrent treatment protocol

Key Trial Info

Start Date :

March 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2013

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT01859689

Start Date

March 1 2012

End Date

September 1 2013

Last Update

July 27 2020

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