Status:

COMPLETED

A Prospective Multicenter Study to Evaluate Usefulness of Cardio-Ankle Vascular Index in Japan

Lead Sponsor:

CAVI-J Study Group

Collaborating Sponsors:

Toho University

Ehime University Graduate School of Medicine

Conditions:

Stroke

Cardiovascular Death

Eligibility:

All Genders

40-74 years

Brief Summary

The objective of this five-year prospective observational follow-up study is to examine the additional benefits of using cardio-ankle vascular index (CAVI) as a predictive indicator of cardiovascular ...

Eligibility Criteria

Inclusion

  • Patients between 40 and 74 years of age who have either of the following:
  • Type 2 diabetes mellitus
  • Metabolic syndrome
  • Grade I to III hypertension with the third layer of risk factors according to the guidelines for the management of hypertension japanese society of hypertension(JSH)2009
  • Chronic kidney disease(stage G3a or G3b) according ot the clinical Practice Guidebook for Diagnosis and Treatment of Chronic Kidney Disease 2012 in Japan
  • History of coronary artery disease or noncardiogenic cerebral infarction

Exclusion

  • Under 40 years of age or over 74 years of age
  • An ankle-brachial index less than 0.9
  • Chronic atrial fibrillation
  • Current symptoms of heart failure(NYHA class III or IV) or left ventricular dysfunction (EF below 40%)
  • Malignancy
  • Chronic kidney disease(G4 or G5)according ot the clinical Practice Guidebook for Diagnosis and Treatment of Chronic Kidney Disease 2012 in Japan
  • chronic dialysis due to renal failure
  • Taking steroids/immunosuppressants
  • Hepatocirrhosis

Key Trial Info

Start Date :

May 1 2013

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 1 2020

Estimated Enrollment :

3026 Patients enrolled

Trial Details

Trial ID

NCT01859897

Start Date

May 1 2013

End Date

April 1 2020

Last Update

September 25 2020

Active Locations (1)

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1

Okayama University

Okayama, Japan, 700-8558