Status:
UNKNOWN
Surgical Resection Versus Percutaneous Local Ablative Therapy for Hepatocellular Carcinoma
Lead Sponsor:
Eastern Hepatobiliary Surgery Hospital
Conditions:
Hepatocellular Carcinoma With CSPH
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The aim of this study is to compare the operative complication and short-/long-term therapeutic effects of percutaneous local ablative therapy (PLAT) versus surgical resection(SR) on small hepatocellu...
Detailed Description
HCC is a major health problem worldwide, with an estimated incidence ranging between 500,000 and 1,000,000 new cases annually. It is the fifth most common cancer in the world and the third most common...
Eligibility Criteria
Inclusion
- 18 Years \< ge ≤ 70 Y,KPS ≥ 70
- A solitary HCC ≤ 5cm in diameter,or multiple HCC(≤3) ,each ≤3cm in diameter without evidence of radiologically definable vascular invasion or extrahepatic metastasis. allowing to both SR and PLAT
- Child-Pugh class A or B,without history of encephalopathy,ascites refractory to diuretics,or variceal bleeding
- NO previous treatment of HCC
- Platelet count\>40,000/mm3；prothrombin time prolongation of no more than 3 seconds
- Patients who can understand this trial and have signed information consent
Exclusion
- metastatic liver cancer
- Patients with apparent cardiac,pulmonary,cerebral and renal dysfunction,which may affect the treatment of HCC
- 3\) Patients with other diseases which may affect the treatment mentioned
- 4） Patients participating in other clinical trials
- 5） Patients with a medical history of other malignant tumors
- 6\) Pregnant and breast-feeding women
Key Trial Info
Start Date :
January 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2016
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT01860222
Start Date
January 1 2011
End Date
December 1 2016
Last Update
March 31 2016
Active Locations (2)
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1
Eastern Hepatobiliary Surgery Hospital
Shanghai, China
2
Eastern Hepatobiliary Surgery Hospital
Shanghai, China