Status:
UNKNOWN
Randomized Controlled Trial to Evaluate High Tie Versus Low Tie of the Inferior Mesenteric Artery in Anterior Resection
Lead Sponsor:
Shoichi Fujii, MD, PhD
Conditions:
Rectal Cancer
Colon Rectal Resection
Eligibility:
All Genders
20+ years
Phase:
PHASE3
Brief Summary
The tying at a radix of the inferior mesenteric artery (IMA) is recognized as radical cure technique in a rectal cancer surgery in Japan. In one side, the preserving the left colic artery (LCA) that i...
Detailed Description
Patients * This was a randomized controlled trial conducted at a single institute, which was Yokohama City University Medical Center (Japan). * 300 patients who underwent anterior resection for recta...
Eligibility Criteria
Inclusion
- Age of 20 years old or over
- Anterior resection is scheduled for rectal cancer and rectosigmoid cancer preoperatively.
- Histologically proven adenocarcinoma
- Clinical tumor penetrates visceral peritoneum (T4a), no metastasis (M0) or lower T factor
- Elective operation
- Tolerable surgery under general anesthesia
- No history of laparotomy for colorectal resection except appendectomy
- Provided written informed consent
Exclusion
- Synchronous or metachronous (within 5 years) malignancy in another organ except carcinoma in situ
- Multiple colorectal cancer that needs reconstruction two or more times
- Acute intestinal obstruction or perforation due to rectal cancer
- Pregnant or lactating women
Key Trial Info
Start Date :
July 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2017
Estimated Enrollment :
331 Patients enrolled
Trial Details
Trial ID
NCT01861678
Start Date
July 1 2006
End Date
September 1 2017
Last Update
August 6 2013
Active Locations (1)
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1
Yokohama City University Medical Center
Yokohama, Kanagawa, Japan, 232-0024